Jini Says: These suppositories contain comfrey – which is a fantastic wound healer. Therefore, they heal anal or rectal fissures amazingly quickly. I’ve used them myself numerous times. Because they’re so long, you can break them into shorter pieces and get 2-3 suppositories out of each one. They’re also extra-thin so no matter how traumatized or sore your rectum is, you can insert them easily.