Jini Says: Be careful when using detox substances to proceed slowly if you are chronically ill - that way you can avoid triggering a flare by doing too much, too quickly. If you are prone to diarrhea, then Bentonite Clay is one of the best detox substances you can use since it will not loosen your bowels, as many of the others will. Don't forget, bowel elimination is one of the body's primary methods of detoxification. If you are suffering from ulceration or intestinal bleeding, then do not do any detox until your system is stronger.